← Shelf·Synthetic tetrapeptide bioregulator·XVI.
Epithalon.
Alanyl-glutamyl-aspartyl-glycine (Ala-Glu-Asp-Gly) — a synthetic tetrapeptide developed by Vladimir Khavinson and colleagues at the St. Petersburg Institute of Bioregulation and Gerontology, first published in the mid-1990s. Also spelled Epitalon.
Positioned in the Russian bioregulator research tradition as a synthetic analog derived from studies of pineal-gland extracts. This is a laboratory-manufactured tetrapeptide, not an extract.
Widely sold with telomere-extension and longevity implications. The primary literature is heavily concentrated in one Russian research group across three decades. Independent replication outside that lineage is limited.
Straight talk
Straight talk: the Khavinson group has published extensively on Epithalon since the 1990s, mostly in Russian bioregulator journals, some translated. Independent Western replication at meaningful scale is thin. Extraordinary claims (telomere lengthening, lifespan effects) have not been established outside that lineage. Read the source group with a scientist's eye.
What the research studies
The literature, not a summary of it.
The Khavinson group's work is where the research lives. Cross-references in Cell Cycle, Bull Exp Biol Med, Neuroendocrinol Lett. Read the research yourself:
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≥ 99% by HPLC on the current lot — ILS Laboratories (ISO/IEC 17025).
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